Notes and Comments #1

by

Ching-Chee Chan, Ph.D.

As Part of the Supplement to

An Alternative Approach to AIDS and Related Problems: Book 2

All Rights Reserved

Egret Publishing Inc.

May 2001

Vaccines and Pretreatments

Since 1960, there have been tremendous increases in incidence rates of immune-related diseases (see Books 1 and 2) and problems with immunological responses to vaccines. lam Many complains about vaccines (pertussis, gan Lymerix, liv anthrax ano ) have been reported.

Not everyone has problems with any one of the vaccines. Therefore, it is an individual thing, regarding the immune system. Some vaccines are more troublesome. Therefore, it also depends on the vaccine: more exotic more lethal, whole cells or just clones of the antigen-containing shell, or the number of required shots.

According to the ENL mechanism (see Chapters 2 & 3, Book 2), stress or intercurrent infection or chemotherapy can cause a compromised immune system, in the presence of the antigens of Hansen's bacteria, to over react, leading to inflammation of blood vessels and tissues. Vaccination or pretreatment is equivalent to intercurrent infection or chemotherapy respectively.

Result of vaccination (or pretreatment) is dependant on the vaccine (or pretreatment) and also the functioning of the immune system as below:

{problems} = {property of vaccine}{status of the immune system}

The product of the two factors, how unsafe is the vaccine and how serious is the immune system compromised, will determine the problem of the vaccination.

Deaths and severe neurological complications due to pertussis vaccination have been reported. gan This is not a surprise, considering large number of people with compromised immune system.

Fever and severe pain in joints and muscle after Lymeris vaccination have been reported. liv People sickened by Lyme vaccine urge FDA action. Ano The symptoms of the reaction due to lyme vaccination are very similar to those of the initial stage of Lyme disease. If Lyme disease is activated by intercurrent infection of B burgdorferi as stated in Chapter 3, Book 2, then a vaccine containing parts of the bacteria, such as antigens, should be able to activate the disease, depending on the dosage of the vaccine and the immune status of the individual. These observed facts are consistent with the hypothesis.

Gulf War Syndrome and Statistics

There are many complaints about the anthrax vaccine. The vaccine is suspected to cause severe skin rashes, chronic bone and joint pain, autoimmune disorders, thyroid damage, seizures, memory loss, neurological problems, chronic fatigue, vertigo, and internal and external lesions. bat, batr Many have left the military because of anthrax shots. ric A study on UK armed forces indicates a weak link between the vaccines and ill health after the Gulf War. hot The UK has too few Gulf War veterans to provide reliable statistics and an independent study should be conducted in the US.

% with GWS symptoms, given age range, 20 - 35 after vaccination and pretreatment should be compared with % with similar symptoms at the same age range without vaccination and pretreatment. This will show whether the vaccine and the pretreatments are responsible for GWS. Most of the victims of GWS are in the US. Therefore, the bulks of the required data are there too. It needs someone familiar with the bureau of statistics (or equivalent) and relevant information in the US to process the data. It is almost certain that anthrax vaccine and the pretreatments were responsible for activating the syndrome.

Vaccines and pretreatments must have been tested and approved before use. During the tests, there must have been test subjects with compromised immune system and ill effects noted, unless the tests were not thorough or involving too few subjects or some of the results were ignored. Fabrications of experimental results are very common in some countries. Many years ago, a fellow-research student informed this author that he could not repeat a result published in a paper because the required concentration of the solution exceeded the solubility of the solute in the solvent at the temperature specified. Independent studies should be carried out in different areas by different groups, funded by different organizations for cross-checking purposes.

References

lam. Lamoureux G. AIDS may be part of a larger phenomenon (letter). Can Research 1987; 20(12): 4.

gan. Gangarosa EJ. Impact of anti-vaccine movement on pertussis control: the untold story (Review). Lancet issue: Jan 31, 1998. FIND articles.com http://www.findarticles.com/m0833/n9099_v351/20351531/p1/article.jhtml

liv. Livni E. Vaccine Victims? abcNEWS.com http://www.abcnews.go.com/sections/living/DailyNews/lyme_vaccine0516.html

ano. Anonymous. People sickened by Lyme vaccine urge FDA action. CNN.com./HEALTH February 2, 2001. http://www.cnn.com/2001/HEALTH/02/02/lyme.vaccine.ap/.index.html

bat. Bates SG. Memorandum for Brigadier General Starbuck. http://www.enter.net/~jfsorg/OfficialDocuments_files/Starbuck.htm

batr. Bates R. Anthrax vaccine plagues Dover AFB. http://www.twoffice.com/integrityfirst/

ric. Rick TE. Anthrax shots cause military exodus.. Washington Post 2000 October 11.

http://www.washingtonpost.com/wp-dyn/articles/A46534-2000Oct10.html

hot. Hotopf M. Role of vaccinations as risk factors for ill healthin veterans of the Gulf war: cross section study. British Medical Journal. http://www.findarticles.com/m0999/7246_320/62918781/p1/article.jhtml

Amyloidosis and High Blood Pressure . . . Etc.

Amyloidosis, which is associated with autonomic neuropathy, inflammatory disorders of unknown aetiology, local or systemic microbial infections, and malignant neoplasms, such as rheumatoid arthritis, Hansen's disease, tuberculosis, Hodgkin's, Alzheimer's and Crohn's diseases, and renal carcinoma, pep may play a role in high blood pressure. Those amyloid plaques can be deposited almost anywhere: the internal wall of blood vessels and the heart. pep The deposits may impede or block the flow of blood. The pumping of the blood may be affected if the plaques are deposited on and inside the heart, resulting in arrhythmia. The combination of all these may cause the blood pressure to rise.

If amyloidosis occurs inside the wall of blood vessels, it may cause the blood vessels to harden and lose its elasticity, hence cause a further rise in blood pressure.

Amyloid deposition can also occur on the skin, in the lungs, urogenital tract, brain, joints, pancreas, linking to diseases such as Alzheimer's, Creutzfeld-Jakob disease (CJD) and diabetes mellitus. pep

The relationship of amyloidosis with several diseases is consistent with the link between Hansen's bacterium and autoimmune diseases or inflammatory diseases or neurological diseases, based on the consideration of the variation patterns in Books 1 & 2.

June 2001

Amyloidosis, Crohn's and Alzheimer's Diseases

According to a report, 80% of the cases of Crohn's disease patients responded to thalidomide treatments (the reference was not recorded). The rest 20% may be presumed to be chronic cases. Thalidomide can prevent overproduction of TNF-alpha. 80% of the patients' problems may be due to inflammation and the rest due to mechanical or structural damages, caused by amyloid plaques. Debates about whether Alzheimer's disease is due to inflammation or the amyloid deposits on the brain are continuing. In view of the treatment results of Crohn's disease patients, both may be the causes. If the pathogen indirectly causing the problems is destroyed, Alzheimer's and Crohn's diseases may be cured.

Amyloidosis may also play a role in tumour formation, leading to fibroid and skin cancer.

References

pep. Pepys MB. Amyloidosis. In: Weatherall DJ, Ledingham JGG, Warrell DA, Eds. Oxford Textbook of Medicine (2nd edition). Oxford: Oxford University Press, 1987: 9.145-9.157.

August 2001

A New book "Plague Time" by Professor Paul W. Ewald

"The harm caused by a gene reduces its representation in the next generation in proportion to the negative effects of the gene on the survival or reproduction of the people who carry it." Ewald wrote. "If we see chronic diseases that have commonly been causing damage for a long time, the best bet is that they have infectious causes." Infection may cause damage directly and as well as through the inflammation it triggers. Inflammation is usually a clue of infection. Atherosclerosis, heart disease, cancers, Alzheimer's disease and impotence are suspected to be caused by infection. A few bacteria and viruses, associated with the diseases, are listed as probable causes. Association does not prove causation. The medical establishment is unwilling to consider research based on infectious causes because the mind is not prepared.

The arguments based on evolution, presented by Ewald, for infectious causes of chronic diseases are convincing. Based on previous works by this author, inflamation and amyloidosis due to Hansen's bacterium are the most likely causes (see the notes and comments above and the links below) for the diseases above except impotence. The human male sexual organ consists of very approximately a vascular system with control valves. If the valves do not shut properly, the correct blood pressure cannot be maintained. What can cause this? The most likely cause or causes are amyloidosis and inflammation. Inflamation may distort the valves. Something deposited at the valve seat will cause the valve to leak. Hansen's bacterium can cause both inflammation and amyloidosis. What is needed is to plot the curve to show the variation pattern whether it is consistent with the variation patterns of those diseases in the previous works but Statistics Canada does not normally provide number of incidence or incidence rates but mortalities due to diseases and nobody has died of impotence. One way to solve the problem is to check for the DNA of Hansen's bacterium in the patient's biological samples by means of PCR or mass spectrometric methods.

The establishment may have another reason for not willing to consider infectious causes for chronic diseases. The media and the establishment like to convey the impression that these diseases are not infectious because the society has to find people to take care of patients of chronic debilitating diseases. They also want to protect these patients from prejudice and evil, harmful ideas. Fifteen or twenty years ago, someone suggested in a Toronto paper that these chronic debilitating diseases might be caused by viral or bacterial infection. He was venomously attacked the next day in the same paper for suggesting it by some president of a foundation or society involving in the care of these patients. Recently there was a TV programme regarding ALS. In the programme, the statement that "it is not infectious" was repeated several times. Patients may have different attitudes. Many readers suffering from these chronic diseases e-mailed this author and they were quite prepared to discuss infection as a probable cause. Perhaps they were not seriously incapacitated and did not need anyone to take care of them. They just wanted to find a way out of their predicament, fooling them that it was not infectious would not help them. Patients are tired of the not-infectious-but-incurable situation. Adopt a practical approach. Communicate directly with patients/readers. The establishment will become irrelevant eventually.

September 4, 2001

Inflammation, Amyloidosis, Fibroid Formation and Bleeding

The variation pattern of the diseases involving the peripheral vascular system has been dealt with, in Chapter 2, Book 1 and in Chapter 3, Book 2, implicating Hansen's bacterium. This bacterium can cause inflammation 43, 44 and amyloidosis. pep If inflammation occurs, leading to thrombosed blood vessels and genesis of new blood vessels (see Rethinking Cancer), and if amyloid plaques are deposited on the same spot, it would look like a fibroid. Perhaps this is the way fibroid is formed.

If inflammation is severe, the blood vessels (capillaries) may leak, leading to internal bleeding. If amyloid plaques are deposited in the wall of the blood vessels (capillaries), it would make it hard and brittle, and it may break easily. Perhaps this is the cause of internal bleeding among the elderly.

Other Probable consequences of damaged blood vessels (capillaries)

The organs and systems depend on the vascular system for supply of nutrients and oxygen and removal of wastes. If parts of the vascular system are damaged, the relevant organs and systems may be affected. Damaged neurological systems may lead to neurological diseases and dementia. Damaged organs (liver, kidneys, pancreas, intestines) may lead to dysfunction and organ failure. Damaged glands may lead to endocrine disorders, diabetes, and hypercalcemia and osteoporosis.

References

pep. Pepys MB. Amyloidosis. In: Weatherall DJ, Ledingham JGG, Warrell DA, Eds. Oxford Textbook of Medicine (2nd edition). Oxford: Oxford University Press, 1987: 9.145-9.157.

January 6, 2002

ALS, Gulf War Veterans, AIDS and Asthma

Some suspect that ALS and AIDS are related because of seven HIV-positive cases of ALS-like syndromes. web Gulf War veterans are almost twice as likely to get ALS than those who did not serve in the Gulf an (see links and references below). Vaccines and pretreatments may have activated Gulf War syndrome, in certain cases resulting in ALS. Some ALS patients complained about asthma on a web board. This author posted a message, suggesting that ALS and asthma might be related. A reader sb responded with e-mail, recounting her experience. This is consistent with the hypothesis proposed, the correlation in the booklets and the Supplement.

References and Links

web. Webmaster. Reversible ALS-like Disorder in HIV infection

http://www.alslinks.com/HTML%20ALS%20Digest/alsd920.htm

Neurology 2001; 57: 945-946; 995-1001; 1094-1097.

an. Anonymous. Trying to prevent another Gulf War Syndrome. CNN.com./HEALTH 2001 December 24.

http://www.cnn.com/2001/HEALTH/12/24/military.health.ap.index.html


Links

High Blood Pressure

Shortened Versions of the Two booklets

Neurological Diseases

Comment on Alzheimer" Disease

Rethinking Cancer

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