Neurological Diseases
Part of Supplement, Book 2
by Ching-Chee Chan, Ph.D.
All Rights Reserved
Egret Publishing Inc., October 1998
The relationship among AIDS, cancer, immune diseases, and the
vascular system has been discussed in Chapter 3, Book 2. All these
diseases have one factor in common; that is inflammation and
leakage of blood vessels. Neurological diseases have similar variation
patterns as those above (Chapter 4), hence they are suspected to be
related to those groups above in similar way: by means of the
vascular system.
A probable mechanism for neurological diseases may be stated as
the following:
A slow infection and overproduction of TNF-alpha lead to
inflammation of blood vessels which leak then become thrombosed,
resulting in blocked or damaged blood vessels. This is called ENL. If
ENL, involving blood vessels or the insulating tissues, occurs near
CNS, blood circulation hence oxygen and nutrient supplies may be
interrupted or reduced and damaged CNS may result, leading to
neurological diseases such as Alzheimer's, Parkinson's and motor
neurone diseases.
Multiple sclerosis does not affect the life expectancy, hence it does
not affect the number of deaths due to M.S., even the incidence rate
changes. Very few data concerning the incidence rates have been
found, hence a proper variation pattern cannot be established.
Judging by the proliferation of organizations dealing with the
disease, the incidence rate may be going up. According to a report
by Midgard and coauthors, the incidence rate by year of onset in
More and Romsdal, Norway, increased from 2.87 per 100,000 in the
period 1950-54 to 5.57 per 100,000 in 1985-91.midgard The disease may
be related to the others immune-related diseases based on the
tentative variation pattern.
Thalidomide can stop overproduction of TNF-alpha, hence it may be
able to prevent or stop neurological diseases such as Alzheimer and
Parkinson's diseases. Some reports indicate that some food
supplements ginkoba have circulation-improving or anti-inflammatory properties are beneficial to Alzheimer's disease and
cerebral palsy may involve cytokines, blood coagulation factors,
inflammation like autoimmune disease.cpalsy Autoimmune disease
may be a kind of ENL of an undetected slow infection.
Alzheimer's disease is known to have developed in person as young
as thirty-nine in the past thirty-eight years. This seems to be a
recent phenomenon. This fits the hypothesis that some neurological
diseases are results of infections and the appearance of a new strain
of a mycobacterium. If a person lives to sixty years old, he will have
three times of opportunity to catch the bacterium than a twenty-years old man. If the new strain is more catching, some twenty-years
old persons may have a reasonable chance to catch the bacterium
and some of them may develop the diseases when they are thirty-nine years old. This may explain the dropping in age of patients.
This may also apply to the lowering of age of cancer patients with
the exception of leukemia.
Notes: motor neurone disease is also known as Lou Gehrig's disease
or amyotrophic lateral sclerosis or maladie de charcot.
The mechanism proposed may also be applicable to endocrine
secretion disorders.
midgard. Midgard R; Riise T; Svanes C; Kvale G; Nyland H.
Incidence of multiple sclerosis in More and Romsdal Norway from
1950 to 1991. An age-period-cohort analysis. Brain 1996 Feb; 119
(pt 1): 203-11.
cpalsy. Anonymous. Cerebral palsy researcher uncovers chemical
link. The Toronto Star 1998 October 1: A32(col1), (col3).
For verification of the hypothesis, see To Find the Actual Cause.